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Cirrhosis represents a late stage of progressive hepatic fibrosis characterized by distortion of the hepatic architecture and the formation of regenerative nodules. It is generally considered to be irreversible in its advanced stages, at which point the only option may be liver transplantation. In earlier stages, specific treatments aimed …Patient Education. UpToDate offers two levels of content for patients: The Basics are short overviews. They are written in accordance with plain language principles and answer the four or five most important questions a person might have about a medical problem. Beyond the Basics are longer, more detailed reviews.The management of bowel obstruction depends upon the etiology, severity, and location of the obstruction. The goals of initial management are to relieve discomfort and restore normal fluid volume, acid-base balance, and electrolytes. Bowel compromise (ischemia, necrosis, or perforation) and a surgically correctable cause of SBO (eg ...UpToDate offers clinical, drug, and patient content to support health professionals wherever care takes place. Learn about subscription options, expert editorial content, access at the point of care, and improved health outcomes with UpToDate.

Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.Allergic conjunctivitis is caused by airborne allergens contacting the eye, which leads to immunoglobulin E (IgE) mediated local mast cell degranulation and allergic inflammation. It typically presents as bilateral ocular itching, redness, and watery discharge. This topic discusses the management of allergic conjunctivitis.The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole). An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here.

INTRODUCTION. —. Acute rhinosinusitis (ARS) is defined as symptomatic inflammation of the nasal cavity and paranasal sinuses ( figure 1) lasting less than four weeks. The term "rhinosinusitis" is preferred to "sinusitis" since inflammation of the sinuses rarely occurs without concurrent inflammation of the nasal mucosa [ 1 ]. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care.

The management of bowel obstruction depends upon the etiology, severity, and location of the obstruction. The goals of initial management are to relieve discomfort and restore normal fluid volume, acid-base balance, and electrolytes. Bowel compromise (ischemia, necrosis, or perforation) and a surgically correctable cause of SBO (eg ...Mar 28, 2024 · Choice of initial therapy in most patients — The three primary options for antihypertensive drug therapy in most patients include an ACE inhibitor (or ARB), a calcium channel blocker, or a thiazide diuretic (preferably a thiazide-like diuretic) [ 3 ]. Access clinical decision support on-the-go with UpToDate's mobile app. Get evidence-based answers to your medical questions anytime, anywhere. Learn more today.About UpToDate UpToDate is the evidence-based, point-of-care resource trusted for reliable clinical answers around the world. UpToDate incorporates the latest medical findings, the best available evidence, and practical recommendations for patient care — so whatever your clinical question, you can be sure to find the answers you need.

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Use the resource trusted by healthcare practitioners worldwide. Patients and their caregivers can learn more about a medical condition and explore treatment options using UpToDate, the same resource trusted by more than 2 million clinicians around the world. After you read the information in UpToDate, you will have the tools and the confidence ...

Mar 28, 2024 ... Outline · Suboptimal response · - Adjunctive CBT · - Pharmacologic management · No response to SRI treatment · Partial response ...Second dose of a 2023-2024 COVID-19 vaccine for individuals 65 years and older (April 2024) In the United States, a single dose of an updated 2023-2024 formula COVID-19 vaccine is recommended for all immunocompetent adults and adolescents, regardless of prior vaccination history. In February 2024, the Centers for Disease Control and Prevention ...Multiple antibiotic regimens have been evaluated for Helicobacter pylori ( H. pylori) therapy [ 1-6 ]. However, few regimens have consistently achieved high eradication rates. There are also limited data on H. pylori antibiotic resistance rates to guide therapy. The treatment regimen that is selected must consider local antibiotic resistance ...The Amazon deals keep rolling out in Cyber Week, with big discounts on Amazon digital media and magazine subscriptions. By clicking "TRY IT", I agree to receive newsletters and pro...Symptoms and signs — Rhabdomyolysis is characterized clinically by the triad of myalgias, muscle weakness, and red to brown urine due to myoglobinuria [ 1 ]. Biochemically, several serum muscle enzymes are elevated, including CK. The degree of muscle pain and other symptoms varies widely. Most of the symptoms of rhabdomyolysis …UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language.Acute pharyngitis is one of the most common conditions encountered in outpatient clinical practice. Most cases of acute pharyngitis are caused by respiratory viruses and are self-limited. However, symptoms of viral pharyngitis broadly overlap with pharyngitis caused by important treatable causes, such as group A Streptococcus (GAS) ( figure 1 ).

Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username.Gastroesophageal reflux becomes a disease when it either causes macroscopic damage to the esophagus or causes symptoms. This topic will review the initial management of gastroesophageal reflux disease (GERD) and management of patients with recurrent GERD when treatment is discontinued. Our recommendations are largely …Pneumococcal vaccination is indicated for adults with risk factors for pneumococcal disease or for severe adverse outcomes should disease occur. Pneumococcal vaccination is also a routine part of infant and childhood immunization schedules worldwide. This topic will review types of pneumococcal vaccines, indications …For over 30 years, clinicians around the world have trusted the evidence-based content in the UpToDate® clinical decision support (CDS) system to help make crucial care decisions when it matters most. Founded by clinicians for clinicians, and backed by an expert editorial team in over 25 specialties, UpToDate provides the latest medical ...May 4, 2023 · The pharmacology, efficacy, contraindications, and side effects of metformin for the treatment of diabetes will be reviewed here. A general discussion of initial treatment of type 2 diabetes and the role of metformin in the prevention of diabetes, in the treatment of polycystic ovary syndrome, and in gestational diabetes are reviewed separately.

INTRODUCTION. Pseudomonas aeruginosa is a key gram-negative aerobic bacillus in the differential diagnosis of a number of infections. This organism is important because it is often antibiotic resistant and can cause severe hospital-acquired infections associated with a high mortality rate, especially in immunocompromised hosts.

Gastroesophageal reflux becomes a disease when it either causes macroscopic damage to the esophagus or causes symptoms. This topic will review the initial management of gastroesophageal reflux disease (GERD) and management of patients with recurrent GERD when treatment is discontinued. Our recommendations are largely …UpToDate support knowledge center. Find answers to frequently asked questions in over 150 fully searchable articles. Search specific keywords or view trending articles. UpToDate customer service and support professionals are available to assist you, or search our self-service help resources for answers to frequently asked questions.The clinical presentation of adrenal insufficiency is variable, depending on whether the onset is acute, leading to adrenal crisis, or chronic, with symptoms that are insidious and vague. The diagnosis of adrenal insufficiency depends upon a critical level of clinical suspicion. Measurements of serum cortisol within three hours after wakening ...Restless legs syndrome (RLS) refers to an urge to move the legs, usually associated with unpleasant sensations. The urge to move the legs is worse at rest and at night and is relieved by movement. RLS is commonly associated with sleep disturbance and with involuntary, jerking movements of the legs during sleep, known as periodic limb …The pericardium is a fibroelastic sac made up of visceral and parietal layers separated by a (potential) space, the pericardial cavity. In healthy individuals, the pericardial cavity contains 15 to 50 mL of an ultrafiltrate of plasma. Diseases of the pericardium present clinically in one of several ways: Acute and recurrent pericarditis.To learn more about UpToDate’s patient information, contact your UpToDate Account Manager or Customer Service. Tel: Email: 1-800-998-6374 [email protected] UpToDate, Inc. | 95 Sawyer Road | Waltham, MA 02453-3471 | www.uptodate.com ©UpToDate, Inc. 12/10 SKU#000250Licensed to: UpToDate Marketing Professional Support Tag : [0502 - 157.55.39.49 - 01006D6174 - PR14 - UPT - 20240515-01:49:19UTC] - SM - MD - LG - XL LoadingGastroesophageal reflux disease (GERD) is notable for its high prevalence, variety of clinical presentations, under-recognized morbidity, and substantial economic consequences. This topic will review the clinical manifestations and diagnosis of GERD. The pathophysiology and management of GERD are discussed in detail separately.The subacute and long-term assessment and management of patients who have suffered a stroke includes physical therapy and testing to determine the precise etiology of the event so as to prevent recurrence. The acute management differs. Immediate goals include minimizing brain injury, treating medical complications, and moving toward …

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The subacute and long-term assessment and management of patients who have suffered a stroke includes physical therapy and testing to determine the precise etiology of the event so as to prevent recurrence. The acute management differs. Immediate goals include minimizing brain injury, treating medical complications, and moving toward …

Contents. You have access to the entire UpToDate® library of specialties with your subscription. Click on one of the specialties below to see sections associated with each. You can also view Practice Changing UpDates, What’s New, Patient Education, Authors and Editors, Calculators, and Drug Information. Practice Changing UpDates.Acute treatment of migraine in adults without hemiplegic or brainstem aura. Algorithm 1. The abortive (symptomatic) therapy of migraine ranges from the use of simple analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen to triptans, antiemetics, calcitonin gene-related peptide (CGRP) antagonists, lasmiditan, …Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here.Access clinical decision support on-the-go with UpToDate's mobile app. Get evidence-based answers to your medical questions anytime, anywhere. Learn more today.Mar 8, 2024 · Beta-lactamases are enzymes that open the beta-lactam ring, inactivating the antibiotic. The first plasmid-mediated beta-lactamase in gram-negative bacteria was discovered in Greece in the 1960s. It was named TEM after the patient from whom it was isolated (Temoniera) [ 2 ]. Subsequently, a closely related enzyme was discovered and named TEM-2. American Association of Nurse Practitioners (AANP) UpToDate is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 051212. For each hour of participation with the UpToDate program, NPs can claim 1.0 contact hour.UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language.Aeromonas species grow at a range of temperatures, although they are isolated with increasing frequency during warmer months (May through October in the Northern hemisphere). Aeromonas species cause a wide spectrum of disease syndromes among warm- and cold-blooded animals, including fish, reptiles, amphibians, mammals, and humans [ 3,4 ].- Advantages and disadvantages of oral anticoagulants - LMW heparin dosing renal insufficiency (adults) - Anticoagulant dose adjustment in liver disease - Possible contraindications to anticoagulation - Standard dosing of DOACs - DOACs PK and drug interactions - Inhibitors and inducers of P-glycoprotein drug efflux - DOAC absorption …Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …Is it postpartum depression or baby blues? It's not the same condition! These are the symptoms of postnatal depression and how to manage them. Postpartum depression is a mental hea...

In February 2020, the World Health Organization (WHO) designated the disease COVID-19, which stands for coronavirus disease 2019 [ 1 ]. The WHO declared an end to the COVID-19 global health emergency in May 2023, more than three years after its emergence. This topic will discuss the virology, epidemiology, and prevention of COVID-19.Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here.Acute pulmonary embolism (PE) is a common and sometimes fatal disease with a variable clinical presentation. It is critical that therapy be administered in a timely fashion [ 1-5 ]. The treatment, prognosis, and follow-up of patients with acute PE are reviewed here. The epidemiology, pathophysiology, clinical presentation, and diagnosis …Instagram:https://instagram. xhp flashtool Use the resource trusted by healthcare practitioners worldwide. Patients and their caregivers can learn more about a medical condition and explore treatment options …UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, … community tv programme The Amazon deals keep rolling out in Cyber Week, with big discounts on Amazon digital media and magazine subscriptions. By clicking "TRY IT", I agree to receive newsletters and pro... how do i clear the cache on my computer CULLEN SMALL CAP VALUE FUND CLASS I- Performance charts including intraday, historical charts and prices and keydata. Indices Commodities Currencies StocksUpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide. New Users. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. ... defender security camera UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. where to watch groundhog day Apr 26, 2022 · Epilepsy is the syndrome of two or more unprovoked seizures that occur more than 24 hours apart [ 1 ]. Seizures affect people in many different ways. Seizures are disruptive in the lives of patients and can cause injury. People with epilepsy have higher rates of psychiatric comorbidity and may experience adverse psychosocial outcomes. super sport Anaphylaxis is an acute, potentially life-threatening, systemic hypersensitivity reaction caused by the sudden release of mast cell mediators [ 1 ]. It most often results from immunoglobulin E (IgE) mediated reactions to foods, drugs, and insect stings, but any agent capable of inciting a sudden, systemic degranulation of mast cells can induce ... mind set Mar 8, 2024 · Beta-lactamases are enzymes that open the beta-lactam ring, inactivating the antibiotic. The first plasmid-mediated beta-lactamase in gram-negative bacteria was discovered in Greece in the 1960s. It was named TEM after the patient from whom it was isolated (Temoniera) [ 2 ]. Subsequently, a closely related enzyme was discovered and named TEM-2. INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in … photos dans icloud UpToDate is an online resource that helps you make informed decisions about medical care. Access the latest evidence, expert opinions, and patient education with your subscription. cool ath UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide. For the best experience, we recommend using the most recent versions of Microsoft Edge, Mozilla® Firefox®, and Google Chrome™. world map A review of the major side effects associated with these agents and the controversy concerning their effect on coronary events, mortality, gastrointestinal bleeding, and the development of cancer are presented here. The management of calcium channel blocker intoxication is presented separately. (See "Calcium channel blocker poisoning" .) ncic com login Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide. For the best experience, we recommend using the most recent versions of Microsoft Edge, Mozilla® Firefox®, and Google Chrome™.